Contains per gram:

Sulfadiazine

Trimethoprim

Description:

The combination of trimethoprim and sulfadiazine acts synergistic and usually bactericidal against many Gram-positive and Gram-negative

bacteria like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Both compounds affect bacterial purine

synthesis in a different way, as a result, of which a double blockade is accomplished.

Indications:

Gastrointestinal and respiratory infections caused by trimethoprim and sulfadiazine sen­sitive micro-organisms, like E. coli, Haemophilus,

Pasteurella, Salmonella, Staphylococcus and Streptococcus spp., in calves, goats, poultry, sheep and swine.

Contra-indications:

Hypersensitivity to trimethoprim and/or sulphonamides.

Administration to animals with a serious impaired renal and/or liver function or with blood dyscrasias.

Side effects:

After long-term treatment and high dosages crystalluria can occur.

When symptoms of crystalluria occur (haematuria, kidney colic), treatment has to be stopped immediately and for example sodium carbonate

(alkalinises) has to be administered for increasing urine solubility of sulfadiazine. Administration for a prolonged period also increases the risk

for blood dyscrasias.

Anaemia, leucopenia and thrombocytopenia.

For oral administration.

Calves, goats and sheep     : Twice daily 5 gram per 100 kg body weight for 4 ‑ 7 days.

Poultry and swine                : 1 kg per 1500 - 2500 litre drinking water for 4 - 7 days.

Note: for pre-ruminant  calves, lambs and kids only.

Withdrawal times

- For meat:

  Swine    : 8 days.

  Poultry : 5 days.

Store in a dark place at room temperature,  protected from light.